Septic cardiomyopathy is a sepsis-induced reversible dysfunction of the heart with a high morbidity and mortality rate, and there are no therapeutic measures based on evidence-based medical support. Conventional treatment includes fluid resuscitation, vasoactive drug application, beta-blockers to reduce sympathetic excitation, anti-infective therapy, and device-assisted therapy.
The main clinical manifestations in patients with septic cardiomyopathy are left ventricular dilatation with normal filling pressures or reduced filling pressures, right ventricular diastolic dysfunction or left ventricular dysfunction, and reduced ventricular contractility or with reduced volume responsiveness. Secondary cardiac involvement may itself be an adaptive mechanism for self-protection, and treatment with cardiotonic drugs should be approached with caution.
The treatment of septic cardiomyopathy is adjusted primarily by hemodynamic assessment to ensure that the needs of organ perfusion are met as a basic requirement. Effective cardiac output and minimum organ perfusion levels are ensured by hemodynamic monitoring.
If you have septic cardiomyopathy, it is important to standardize treatment as prescribed.