When colchicine is overdosed during gout attack, patients may experience adverse reactions such as diarrhea, liver and kidney function impairment, and patients should seek medical attention promptly.
Colchicine is a class of drugs in the acute attack of gout, can effectively inhibit the neutrophil repulsion, adhesion and phagocytosis, to achieve the purpose of controlling the local pain, swelling and inflammatory reaction of the joints. So it is used for the pain and other discomforts of acute attacks of gouty arthritis.
Colchicine as a prescription drug should be used in strict accordance with the doctor’s instructions, there are liver and kidney function injury, myeloproliferative hypoplasia or pregnancy, lactation, allergic to the product is prohibited.
Because colchicine is a cytosolic mitotic toxin, toxicity, once overdose, the lack of appropriate special detoxification measures, need to pay extra attention to the dosage.
Gout attack period colchicine dosage is too large, patients may have diarrhea, liver and kidney function injury and other adverse reactions, patients should seek medical attention in time, monitoring blood as well as liver and kidney function. Mainly take symptomatic treatment, for example, liver injury take polyene phosphatidylcholine, glutathione and other liver protection therapy, drink more water to promote drug metabolism and so on.
It is recommended that patients with excessive colchicine use during gouty attacks should go to the rheumatology and immunology departments of regular hospitals for detailed consultation and standardized treatment according to the doctor’s instructions.