Whether male or female, under normal circumstances blood uric acid will not exceed 380umol/L. Clinically, uric acid >420umol/L can be diagnosed as hyperuricemia, and uric acid 427umol/L has reached the standard of hyperuricemia. At this time, we need to look at the situation separately. If the patient has already had a gout attack, then in the acute phase of the gout attack, we should focus on anti-inflammatory, analgesic and joint pain relief treatment. If the acute phase is over, it can be controlled with appropriate uric acid-lowering medication during the interval. If you have simple hyperuricemia without gout and uric acid reaches 427umol/L, you should first review your diet to see if you have a high purine diet and pay attention to seafood, animal offal, beer and soy products. If there is no contraindication, take sodium bicarbonate, which is commonly known as baking soda, to alkalize the urine and promote the excretion of uric acid in the urine to reduce blood uric acid. If uric acid keeps rising gradually without decreasing, it is still necessary to seek medication to control uric acid.