Closed-cell pimples belong to a type of acne lesions, which may be related to increased sebum secretion, bacterial infection, abnormal keratinization of follicle cells, etc. Closed-cell pimples on the chest can be improved through general treatment, medication and physical therapy. 1. General treatment: patients should develop good habits, ensure regular life, avoid staying up late, pay attention to skin cleaning. They should also have a light diet, avoiding spicy and stimulating, high sugar, high fat and other types of food, such as chili peppers, fried chicken, cakes and so on. 2. Medication: patients can use retinoic acid drugs, such as adapalene gel, tazarotene cream, etc.; antibiotics, such as erythromycin ointment, clindamycin gel, fusidic acid cream, etc.; also with the use of benzoyl peroxide, azelaic acid ointment for treatment, but also oral minocycline, isotretinoin, prednisone and other drugs, in order to improve the condition. 3. Physical therapy: Physical therapy mainly adopts photodynamic therapy to reduce the inflammatory response, and can also be combined with the application of red and blue light irradiation to promote the recovery of skin lesions. It is recommended that patients strictly follow the doctor’s instructions to use medication, do not change the dose of drugs or private abuse of drugs, so as not to cause adverse reactions.