Pain is an important signal that the human body is ill and it reminds people that they should go to the hospital promptly, which is the beneficial side of pain for the human body. However, in the vast majority of cases, pain can bring serious harm to the body and even cause catastrophic consequences. Mild pain can cause mental suffering, affect diet and living, and lead to a decrease in quality of life; severe pain will cause dysfunction of various systems, low immunity and induce various complications, and even lead to painful disability or affect the life of the patient. In reality, it is not uncommon for patients to suffer from chronic pain for a long period of time, resulting in a variety of illnesses and even lightness of life. Therefore, it is a very old-fashioned and harmful misconception that pain is not a ‘disease’ and does not need to be treated specifically. Timely diagnosis and treatment of pain and effective pain control is an important part of life’s health. With the advancement of medicine, pain research and treatment has entered a specialized stage of development. Modern medical research has shown that many chronic pains are diseases in themselves, not just a symptom. Pain often coexists with other diseases or can appear alone, and pain problems need to be treated with a professional attitude and managed with professional means. In the past, the piecemeal and reactive pain management model of different clinical specialties was far from adequate to meet the clinical needs. In this context, a new discipline, pain management, was born and has been developing rapidly. Under the guidance of modern pain theory, the pain treatment specialist conducts a new mode of comprehensive analysis and treatment for pain diseases and difficult pain problems encountered in clinical medicine. We have perfected the treatment of many painful diseases that are difficult to control. For common chronic pain diseases such as head and face pain, cervical spondylosis, frozen shoulder, intervertebral disc lesion, lumbar back and lower limb pain, nerve block, nerve stimulation, drugs and other comprehensive therapies can effectively improve the local blood circulation disorder of pain, remove inflammatory metabolites, interrupt the vicious cycle of pain, so as to achieve the effect of “treating both symptoms and root causes”. “The analgesic effect can be achieved by removing the metabolic products of inflammation and interrupting the pain cycle. For herpes zoster and its sequelae pain, trigeminal neuralgia, sciatica, phantom limb pain, burning pain and other intractable neuronal pain, specific nerve block technique and nerve frequency (thermal) electrical modulation stimulation are applied to block nociceptive conduction pathways, improve nerve nutritional status and adjust nerve conduction function, achieving satisfactory pain treatment results. For cancer pain, the latest foreign cancer pain control methods are applied to combine with the patient’s physical condition and pain site, and the nerves conducting pain are highly selective blocked or destroyed, which can achieve more perfect medium and long-term analgesic effects in one treatment. The advantages of this method for cancer pain treatment are that it can minimize the common side effects in traditional cancer pain treatment, and it has positive effects on relieving patients’ adverse emotions such as fear, anxiety and depression caused by cancer pain, enhancing appetite, improving sleep and improving their quality of life. In addition, the unique means of pain treatment can be applied to certain non-painful diseases such as chronic rhinitis, sudden deafness, retinopathy, insomnia, persistent erratic, dysmenorrhea, chronic fatigue syndrome, etc., and can also achieve more satisfactory results.