Lung nodules visible lobulated pleural depressions require puncture biopsy of lung nodules, malignant nodules can be surgically resected, and benign nodules can be temporarily observed. As the lung nodule visible lobular pleural depression, suggesting that the possibility of lung tumor is very high, and the degree of malignancy is high, need to further improve the relevant examination, such as chest puncture biopsy, according to the biopsy results to determine whether it is a benign or malignant nodule. For patients with malignant lung nodules, surgical resection of the nodules and postoperative radiotherapy are important for prolonging the patient’s life and improving the quality of life. For patients with benign nodules, if they do not have clinical symptoms, they can be observed, and abdominal CT should be repeated every 3-6 months to observe the changes in the diameter of the nodules. If the diameter of the nodules is large, it is recommended to have them removed surgically at an early stage to avoid malignant transformation of the benign nodules. Lung nodule patients, usually if there is discomfort, timely to the hospital, do not be careless, so as not to miss the best time for treatment.