Pneumonectomy patient sputum can eat acetylcysteine effervescent tablets, eucalyptus-pinocampus enteric soft capsule, etc., specific need to follow the guidance of the physician. Pneumonectomy patients, often due to cerebrovascular accidents or severe infections such as the use of ventilators after pneumonectomy treatment, often due to local irritation of the cannula or chronic inflammation of the lungs stimulate the production of more sputum, according to the condition of the patient can be given to the oral phlegm removing drugs, such as acetylcysteine effervescent tablets, eucalyptus-pinol enteric softgel capsule, and so on. If the sputum is caused by acute lung infection, anti-infective drugs such as cephalosporins, penicillins and other antibiotics should be taken or used intravenously. Specific medication regimen should follow the physician’s instruction. Acetylcysteine effervescent tablets may cause headache, tinnitus, tachycardia, vomiting and other adverse reactions, is prohibited in allergy and phenylketonuria patients; eucalyptus-pinocampus enteric soft capsule may cause gastrointestinal discomfort, skin rashes, etc., is prohibited in allergic patients. Pneumonectomy patients with sputum recommend timely medical care, improve the relevant laboratory tests, follow the doctor’s instructions for medication, avoid blind self-medication.