The main treatment for chronic urticaria is the use of H1 receptor antagonists and H2 receptor antagonists for treatment, generally the use of two different types of drugs with the application, such as deslorpromazine or Antares plus Cyproheptadine, etc. You can also use a new generation of antihistamines for treatment, such as Epastine, loratadine, cetirizine, such can be used. H2 receptor antagonists can be used metformin, or ranitidine. The H2 receptor antagonist can be metacamidine or ranitidine. Tricyclic antidepressants are mostly used in the form of doxepin, which is taken orally 2-3 times a day. Patients who do not respond to conventional antihistamines can use other types of drugs, such as cerebrolysine, aminophylline, reserpine, placental tissue fluid, which can be used.