Cough without sputum, also known as dry cough, caused by cough without sputum for many reasons, commonly found in cough variant asthma, chronic pharyngitis, gastroesophageal reflux cough and so on. 1. Cough variant asthma: it is a special type of asthma, which is mainly characterized by irritating dry cough, mostly occurring at night and in the early hours of the morning, without obvious symptoms such as wheezing and shortness of breath. It can be treated with inhaled glucocorticosteroids (e.g. budesonide) and bronchodilators (e.g. salbutamol) under doctor’s guidance. 2. Chronic pharyngitis: The causes of chronic pharyngitis include bacteria, environment and occupation, etc. Symptoms include dry cough, foreign body sensation in the pharynx, and sore throat, etc. It can be treated by taking medicines such as clearing throat granules, pharyngitis tablets, etc. under doctor’s instruction. 3. Gastroesophageal Reflux Cough (GERD): a clinical syndrome in which coughing is a prominent symptom due to the reflux of gastric acid and other gastric contents into the esophagus. Omeprazole, rabeprazole, mosapride and other drugs can be used under the guidance of the doctor. There are many causes of cough without sputum, it is recommended that patients go to the hospital in a timely manner to clarify the cause of the disease, under the guidance of the doctor for treatment.