The main symptoms of monkeypox virus infection are rash and fever. Monkeypox virus was first traced back to 1958 and was isolated from laboratory animals (monkeys). The incubation period of monkeypox virus is about 1 to 2 weeks, followed by clinical symptoms. The prodromal period (usually 2 to 5 days) is characterized by fever, general malaise, fatigue, headache, myalgia, back pain, and also sore throat. Usually 1 to 3 days after the onset of fever, a rash may appear, initially maculopapular, which is characterized by ovoid to annular red bumps; then develop into herpes, forming small pustules, often accompanied by local lymph node enlargement. The rash usually begins on the face and spreads in all directions. In addition, the rash may also appear in the mouth and genitals. If you are infected with monkeypox virus, you should go to the hospital in time, and under the guidance of the doctor to actively treat the disease, so as not to delay the condition.