How the success rate of in vitro fertilization is calculated

The first thing we need to be clear about is that success rates vary from person to person. With the same doctor, ovulation process, equipment for culturing embryos, and operators, success rates can vary greatly from patient to patient. The biggest reason for this is that the physical conditions of two people are different. Physical conditions include many factors of both spouses: the age, ovarian function, egg maturity, and uterine environment of the woman, the sperm activity and malformation rate of the man, and the developmental status and potential of the embryo before implantation. In particular, the intrauterine environment at the time of embryo implantation is very important for embryo implantation. Even in people with very similar age and ovarian function, the intrauterine environment may be very different in different menstrual cycles. Therefore, the success rate is closely related to each individual’s specific situation. The most common method of calculation is the “clinical pregnancy rate”. This is simply “number of pregnancies / number of cycles”. For example, if an institution has performed 100 transplants (cycles) and 50 pregnancies, then the clinical pregnancy rate is 50%. This success rate is simple and easy to understand, but the drawback is obvious: there are some people who miscarry after IVF pregnancy, and the success rate calculated by using pregnancy as the success indicator is definitely high. Another commonly used one: the live birth rate. It is: number of live births / number of transplant cycles. For example, if an institution has done 100 transplants (cycles) and 30 of them resulted in a surviving baby, then the live birth rate is 30%. This indicator is closer to the psychological expectations of patients and more reflective of the true level of an institution. Other calculations are: biochemical pregnancy rate: number of biochemical pregnancy cycles/number of transfer cycles X 100%; implantation rate: number of gestational sacs/number of embryos transferred X 100%; persistent pregnancy rate: number of persistent pregnancy cycles/number of transfer cycles X 100%; these indicators are often used more for the description of scientific data. With so many doors in success rates, what should we think about success rate data and rankings? What to make of IVF success rates and rankings: Because of their simplicity and intuitiveness, various organizations are willing to present success rates for potential clients to refer to. The average client should still use this number as a reference indicator to understand the general performance of the organization in question, but should never be superstitious, and even beware of organizations that only present success rates. If possible, provide an examination report for your own situation so that you can get an estimate that is completely specific to your situation. (For example, a 38 year old mother-to-be with diabetes is looking at the IVF success rate of a 30 year old healthy woman for half a day, which is really meaningless~). A few final tips for you: don’t believe in success rates, get your own individual diagnosis as soon as possible. The younger you are, the better the odds, regardless of other conditions! Whenever you are considering IVF, you must do it while you can. Knowing all this, parents-to-be should never get discouraged, why not see what the success rate of natural pregnancy is: “Healthy women aged 20-30 years have a pregnancy rate of only 20-25% in an ovulatory cycle, and only 5-18% in 35-40 years”. You see, even with natural pregnancy, the chances of success are not at all as high as we might think.