Cerebral artery wall is rough, the lumen is unevenly thick and thin treatment to use drug therapy, life behavior, interventional surgery and other comprehensive therapy. 1. Drug therapy: anti-platelet drugs can be taken, such as aspirin enteric-coated tablets, clopidogrel, etc., anti-atherosclerotic drugs such as Rosuvastatin, atorvastatin, etc.. 2. Behavior: It is necessary to change the bad habits such as smoking, drinking, staying up late, etc.; light diet, eat less oil, salt food; appropriate exercise, keep a good mindset, and ensure enough sleep. 3. Interventional surgery: If the condition of blood vessels deteriorates, resulting in severe stenosis, stent implantation surgery will be performed according to the situation. Cerebral arteries with rough walls and uneven lumen indicate poor intracranial vascular condition, which is prone to cerebrovascular accidents. It is recommended to consult a doctor in time, and interventions and treatments should be carried out under the guidance of a professional physician, and do not blindly self-medication.