Frequent twitching of the legs at night in bed may be related to the following causes: 1. It may be caused by electrolyte disorders. This condition is often seen when the patient has a lot of sweating or a lot of vomiting or diarrhea before, which causes the loss of digestive fluid. This may cause the electrolyte level in the body to be disturbed, which may lead to frequent muscle twitching; 2. It may be caused by severe osteoporosis. This condition is often seen in elderly patients with osteoporosis, especially elderly women, and may cause significant pain in the lower limbs when the disease strikes, and accompanied by continuous cramps; 3, may be caused by serious peripheral nerve lesions, such as sciatica or lumbar disc herniation is very serious, may frequently cause radioactive pain in the lower limbs, and accompanied by muscle 4, may also be caused by the patient to do too intense activities, such as the patient in the competitive sports activities to do very intense, and continuous, high intensity activities, then at night rest may also appear this situation; 5, this situation may also be due to the patient’s high mental tension, high excitement caused by.