Symptoms of chronic cough and wheezing are likely to be chronic bronchitis. A chest CT is needed to confirm the diagnosis. If it is indeed a case of chronic bronchitis, anti-infective treatment is needed during the acute phase of the attack, starting with sputum culture and drug sensitivity testing. According to the type of infection, choose the appropriate antibiotics for anti-infection treatment. Secondly, cough and sputum treatment and asthma treatment should be carried out. For cough and sputum treatment, you can choose aminoglutethimide oral solution or aminoglutethimide hydrochloride, and the effect of compound fresh bamboo liquid is also good. As for asthma medication, you can nebulize and inhale some bronchodilators and glucocorticoids to calm asthma, such as budesonide and terbutaline sulfate. Another kind of long-term cough and wheeze may be caused by asthma, which requires long-term anti-asthma treatment, such as chewing a chewable tablet of montelukast sodium before going to bed, and long-term inhalation of Cymbalta to relieve symptoms.