Phenylethylamine is an alkaloid and monoamine neurotransmitter with neurotransmitter effects, and its derivative compounds are used as drugs. Phenylethylamine is also a natural compound that can be present in foods, such as chocolate, Phenylethylamine elevates extracellular fluid dopamine levels and modulates noradrenergic transmission. When the benzene ring, side chain, and amino group of phenethylamine are replaced, various phenethylamine compounds can be generated to make a variety of clinically used drugs, such as catecholamines (including norepinephrine, epinephrine, and dopamine), which are generated by substituting hydroxyl groups at the 3,4 position of the benzene ring. Common drugs such as bronchodilators (salbutamol) and antidepressants (bupropion) are chemically synthesized from phenethylamine. Phenethylamine and its compounds need to be used under the supervision of a medical professional.