Patients who wake up with swollen eyes after sleeping may have the following conditions, and can take appropriate treatment measures according to the specific situation: First, mydriasis: it is an acute inflammation of the lid gland, mostly caused by Staphylococcus aureus infection, and can be treated by timely prescription of appropriate antibiotic-type eye drops, such as tobramycin eye drops and ofloxacin eye drops. Local hot compresses can also be applied, wheals swelling with pus tip can be picked open to drain the pus treatment. Second, allergy: allergic reactions to cosmetics, pollen and other allergens can lead to swollen eyes, which require timely anti-allergic treatment, often choosing anti-allergic eye drops, such as olopatadine hydrochloride eye drops, azelastine hydrochloride eye drops, sodium cromoglycate eye drops, etc. Those with obvious eye swelling can also take oral anti-allergy drugs. Third, other: eye swelling may be caused by poor rest, staying up late, crying a lot before going to bed, depending on the specific situation, to improve lifestyle habits, you can apply cold towel ice packs locally on the eyelid area to relieve the swollen eyes. Fourth, systemic diseases: eye edema may also be caused by systemic diseases, such as kidney disease, nephrotic syndrome, glomerulonephritis, proteinuria, hematuria, etc. In addition, there are systemic diseases such as hypothyroidism, severe anemia, hypoproteinemia, etc. Some corresponding systemic examinations can be carried out to clarify the cause, and active treatment can be carried out according to the cause.