The first step is to exclude intracranial organic lesions, and cranial MRI should be examined to clarify the diagnosis. If organic lesions are excluded, symptomatic pain treatment should be given, mainly with oral ibuprofen, indomethacin and naproxen, and also with acetaminophen, aspirin and diazepam. If the above treatment is not effective and the headache is severe, ergotamine caffeine can be given orally. If the patient still has headache after the above treatment, zolmitriptan and sumatriptan can be applied. Calcium antagonists are often applied clinically, and the main drugs commonly used are nimodipine. If the patient still has headache without significant relief after the above-mentioned comprehensive treatment, oral prednisone 20-30mg can also be applied orally at once, together with sedative drugs. After the above-mentioned comprehensive treatment, patients will generally have significant relief of headache. Cluster headache and migraine are a kind of primary neurovascular headache, the exact cause of the disease is not clear, and symptomatic treatment is mainly given.