The blisters on the feet may be tinea pedis, eczema, hand, foot and mouth disease, etc., and can be improved by medication. 1. Tinea pedis: mostly caused by fungal infections, may appear foot long blisters, accompanied by itching, etc., blisters subside can appear after flaking. Need to keep feet and shoes clean, can be used topical terbinafine, ketoconazole and other drugs antifungal treatment, serious symptoms also need to follow the doctor’s advice oral terbinafine, itraconazole and other antifungal drug treatment. 2. Eczema: the cause of the disease is not known, is inside and outside the inflammatory skin disease caused by multiple factors. When there is no exudation of skin lesions, mometasone furoate and other glucocorticoid ointment can be used externally; when exudation of skin lesions occurs, it is necessary to use boric acid solution and other wet compresses, to be localized without exudation, glucocorticoid ointment can be used externally; it can also be prescribed oral loratadine and other antihistamine medication. 3. Hand, foot and mouth disease: most common in infants and children, caused by enterovirus infections, can appear in the foot red maculopapular rash, herpes, etc., blisters can appear after the subsidence of desquamation, often accompanied by fever and so on. Usually given antipyretic, rehydration and other symptomatic supportive treatment; if the symptoms are serious, involving the respiratory and circulatory system or the nervous system, it is necessary to go to the hospital in time for emergency treatment. The blisters on the feet may also be caused by other diseases, it is recommended that patients go to the hospital in a timely manner, after a clear diagnosis under the guidance of the doctor’s standardized treatment, at the same time, the above mentioned drugs need to be used under the guidance of a doctor.