Leg cramps after cerebral thrombosis should be treated symptomatically according to the cause. If the cerebral thrombosis is a large cerebrovascular, cortical area cerebral thrombosis, and the patient has weakness of one side of the limb, and there is a twitching of the leg on the affected side, an EEG should be done to monitor to see if there is any epileptic seizure. If the seizure is secondary to epilepsy, carbamazepine or sodium valproate oral antiepileptic drugs can be given and the symptoms can be relieved. If the overall condition of the patient is poor after the cerebral thrombosis, and the patient can not eat or rely on nasal feeding diet, which will cause nutritional absorption and intake obstacles, and it is easy to cause hypocalcemia, and need to go to the hospital to do blood calcium monitoring. If the leg cramps are caused by hypocalcemia, the symptoms can be relieved after calcium supplementation. Therefore, leg cramps after cerebral thrombosis should be treated according to the specific situation.