In 2019, Bayer announced the approval of Vaisanin (denogestrel tablets), a new drug for the treatment of endometriosis, in China. Vaisanin is a tablet containing 2 mg of denogestrel and is the world’s first progestin developed specifically for the treatment of endometriosis. For the launch of this drug, it brings new hope to the majority of endometriosis, adenomyosis patients. However, due to various factors such as surgery and consultation, I have not been able to compile the relevant information. Today, at the request of patients with adenomyosis, I am organizing and answering questions about Vaisanin for adenomyosis. Vaisanin, also known as Denogest, costs about 530-680 RMB on the mainland, and the price is still relatively cost-effective compared to injections. However, compared to other painkillers or on the Manmole, but … The main feature of this drug is better efficacy, is 17-34 times more than the progestin we used to eat, that is to say, the same dose, its efficiency is very high, so as to effectively improve the pain, at the same time because it is a relatively small dose, long-term use of the side effects are relatively It is also effective in improving pain, and because it is a smaller dose, the side effects are relatively lower when used for a long time than others. The disadvantage is that long-term management and long-term use of the drug can only relieve the condition, but not cure adenomyosis. Vaisnavas should be taken orally, one tablet daily without interruption, preferably at the same time every day, with water when needed, after meals or on an empty stomach, and the tablets must be taken continuously (this is also the disadvantage of the drug). Vesanin can be started on any day of the menstrual cycle. You need to stop using any hormonal contraceptives before you start taking the pill orally. If contraception is needed, non-hormonal methods (such as condoms) should be used. The most common side effect of Denogestrel (Vesanin) is spotting and bleeding at the beginning of the drug. During the first six months of use, more than half of the patients will experience irregular bleeding or even increased menstrual flow. However, it will gradually decrease as the duration of the drug increases. Other common side effects include headache and breast tenderness at the beginning of the drug. Feedback from patients who have taken Vaisanin: “I used to have pain for a few days when I had my period, but no pain at all at other times. Since taking Vaisanin, I started to bleed every day on the thirteenth day and my abdomen hurt and swollen like menstrual cramps, but my period was not yet due.” “I’ve been taking Vaisanin for 120 days and I’ve been bleeding every day. I started bleeding half an hour after taking the pill, almost the amount of a sanitary napkin. The next month indicators, it really can not be helped or the surgery” From their feedback can be seen, oral Vesanine is actually not a perfect treatment plan, some people may relieve menstrual pain, but some people are not applicable. There is no drug that can completely cure adenomyosis, and the main purpose of using drugs is to relieve pain and reduce bleeding. The solution to cure adenomyosis is still surgical treatment. There are two main types of surgical treatment, one is conservative surgery, which is adenomyosis lesion removal, that is, uterine preservation surgery. The surgery will resolve adenomyosis lesions, adenomyoma lesions, even combined coeliac disease, abdominal wall ectopia, and uterine fibroids all together. The uterine-preserving surgery was developed in the year 2000 or so, with continuous experience and integration of research. So far, the uterus-preserving surgery not only preserves the uterus and completely removes the focal tissue, but also, on the basis of this, provides better incisions, separation of intraoperative adhesions, intraoperative hemostasis, removal of endometriosis foci, suturing method, protection of the endometrium, revision of the uterine cavity shape, and postoperative uterine repair and anti-adhesion. The procedure is less invasive, reduces the recurrence rate, and preserves fertility. The surgery not only preserves the patient’s uterus, but also allows for the disappearance of dysmenorrhea, the disappearance of symptoms caused by adenomyosis, normal menstruation, and the slow return to normal after surgery for patients with anemia due to heavy menstruation. There is another type of surgery, radical surgery, which is the removal of the uterus, which I am sure we all know more or less well.