Whether high creatinine can be cured or not depends on the cause of high creatinine: 1, if it is due to acute glomerulonephritis, caused by a transient high creatinine, most of the patients can be cured because acute glomerulonephritis has the tendency of self-healing, and creatinine will be reduced to normal within 6-8 weeks. 2, if it is due to acute progressive glomerulonephritis, because acute progressive glomerulonephritis has a higher case fatality rate, after active treatment, some patients will turn into chronic kidney failure, so the probability of cure is relatively small. 3, if it is due to acute kidney failure, such as chronic kidney failure, some of the patients will turn into chronic kidney failure. If acute glomerulonephritis causes high creatinine, because acute glomerulonephritis has a high morbidity and mortality rate, some patients will turn to chronic renal failure after active treatment, so the probability of cure is relatively small. 3, if acute renal failure causes high creatinine, for example, there is a urinary obstruction that causes blood creatinine to rise suddenly, and creatinine can be restored to normal after lifting the obstruction. 4, if chronic renal failure causes high creatinine, such as the uremic stage that the ordinary people often say, the patient with high creatinine can’t be helped. There is no way to cure high creatinine unless the patient has a new kidney, and if the patient is on hemodialysis or peritoneal dialysis, the patient’s life can only be maintained, and the disease can not be completely eradicated.