What is the difference between children and adults with the same meningioma?

Meningiomas are extremely rare in childhood, accounting for only 0.4% to 4.6% of childhood intracranial tumors. Children’s meningiomas and adult meningiomas are both brain tumor diseases, some people may think that they can know the difference between these two diseases from the literal look, that is, the onset of the two diseases is not the same population, children’s meningiomas are onset in children and adult meningiomas are onset in adults. In fact, the difference between these two brain tumor diseases is much more than that. The difference between children’s meningiomas and adult meningiomas 1, adult meningiomas are mostly benign, sarcomatoid lesions are rare, while children’s intracranial meningiomas are more malignant than adults. Located in the triangle of lateral ventricle and posterior cranial recess: adult meningiomas occur in the cerebral protuberance or sagittal sinus, while in childhood, the tumor is mostly located in the triangle of lateral ventricle and posterior cranial recess. 2.Children with meningioma are often combined with neurofibromatosis. Endothelial type and vascular endothelial cell type are common. Adult meningiomas are more common in fibrous type and gravel type, while children are more common in endothelial type and vascular endothelial cell type. 3.Adult meningiomas tend to grow slowly and have a long course of disease, while children’s tumors often grow faster, and the tumors may be huge at the time of diagnosis. 4.Adult meningiomas mostly have adhesion with dura mater; in children, there are few tumors without adhesion with dura mater, which may be related to the tumor from arachnoid or soft meninges. Calcification is rare in children’s meningiomas, and cystic changes and hemorrhage are common. Higher recurrence rate: The recurrence rate of postoperative meningioma in children is higher than that in adults. Location: Intracranial arachnoid granules and arachnoid villi are the most common sites of meningiomas; 2. Parasagittal sinus, cerebral convexity, and cerebral falx are also more common; 3. Pterygoid crest, saddle nodes, olfactory groove, cerebellar pontine angle and cerebellar pallidum are less common; 4. Meningiomas growing inside the ventricles of the brain are rarely seen. Pathogenesis The occurrence of meningioma may be related to certain changes in the internal environment and genetic variations, and is not caused by a single factor, but may be related to craniocerebral trauma, radioactive irradiation, viral infection, and the combination of bilateral acoustic neuroma and other factors.