The patient, male, 58 years old, was admitted to the hospital with “obstructed feeding with dyspeptic symptoms for 1 month”. He had been suffering from vitiligo for more than 10 years, no smoking or drinking habits, denied history of tumor and other special diseases. Physical examination: no enlargement of peripheral lymph nodes; scattered white spots on the skin of head, face and limbs; no special heart and lung; flat and soft abdomen, liver and spleen are not large, and the rest are not abnormal. Laboratory examination: tumor markers CEA, aFP, etc. were normal. Barium swallow and barium meal examination of the stomach suggested a huge irregular filling defect in the middle and lower esophagus with dilatation of the diseased esophagus. Gastroscopy revealed a pendulum-shaped, partially black, polypoid mass with an unsmooth surface and a shallow ulcer, about 10 cm long, with the tip attached to the posterior wall of the esophagus at 25 cm from the incisor. Biopsy suggested malignant melanoma. An esophageal tumor resection + supragastric aortic arch anastomosis was performed, and the postoperative recovery was good.