Blistering of the soft palate of the mouth can be caused by eating irritating foods, pathogen infections, and other causes. Oral soft palate blistering may be caused by eating irritating foods, such as eating chili peppers, ice cubes, drinking hot water, or eating particularly hard foods, which can cause direct physical and chemical irritation to the mucous membrane of the palate, resulting in blisters, or even blood blisters, on the mucous membrane of the palate. Oral soft palate blistering may be caused by pathogen infection, which mostly occurs in the elderly and children with low immunity, or patients wearing removable dentures, in which the mouth is infected by Candida albicans causing redness, swelling, inflammation, and blistering of the palate mucosa. Oral soft palate blistering patients should go to the hospital in time to confirm the diagnosis, under the guidance of the doctor for standardized treatment. At the same time to drink more hot water, eat less spicy and stimulating food.