Patients with novel coronavirus infection can reduce fever after fever. Novel coronavirus infection is mainly characterized by fever, dry cough and fatigue, and fever is mostly high, with body temperature more than 38.5°C. Patients are prone to recurrent fever symptoms, and even if they are treated to reduce fever, fever will appear again if the disease is not effectively controlled. When patients with novel coronavirus infection are treated with antiviral drugs, and actively prevent and control the corresponding infection, and strengthen symptomatic treatment, the disease gradually remits, and the fever will gradually subside. However, it should be noted that such patients have reduced resistance and are prone to secondary bacterial mixed infections. When they develop fever again or have high fever that is difficult to control, it is necessary to exclude the presence of bacterial sepsis and bacterial pneumonia and other mixed infections, to improve the corresponding examination in a timely manner, and then to enhance the treatment of the corresponding anti-infective drugs.