Common glimepiride drugs include glimepiride tablets, glimepiride dispersible tablets, glimepiride capsules, etc., generally does not cause harm to the kidneys, the patient will mainly cause irritation to the gastrointestinal tract after using the drug, it may also induce allergic reactions, but the patients who are severely impaired in their own renal function are not recommended to take this drug. Glimepiride is a kind of hypoglycemic drug, mainly used for the treatment of type 2 diabetes mellitus, patients may cause gastrointestinal tract stimulation, nausea and vomiting, abdominal pain and diarrhea, and may also induce allergic reactions, such as itching, skin erythema and so on. It is not recommended to take this drug for patients whose own renal and hepatic functions are severely impaired, because the kidneys are the excretory organs of the human body and need to metabolize the substances produced by the drug, and it is not conducive to the recovery of renal function in patients with severely impaired renal function after the use of the drug. Patients need to take Glimepiride under the guidance of a doctor, avoid unauthorized use of the drug treatment.