It is recommended to discontinue antibiotics for one week before receiving the human papillomavirus (HPV) 9-valent vaccine. Before receiving HPV 9-valent vaccine, it is not recommended to receive the vaccine if the following conditions exist: allergy to the active ingredients or excipients of the vaccine; suffering from acute diseases, severe chronic diseases, exacerbation of chronic diseases, and fever: preparing for pregnancy, pregnant and breastfeeding women; applying antibiotics within one week, receiving other vaccines within two weeks, and using blood products in three months. HPV nine-valent vaccine is applicable to women aged 9~26 years old, which can cover nine types of human papillomavirus 6, 11, 16, 18, 31, 33, 48, 52, 58 human papillomavirus, and can prevent 90% of cervical cancer, condyloma acuminatum, vaginal cancer, anal cancer, etc. It is recommended that women without contraindications to vaccination should actively receive the vaccination.