Blood tests cannot detect syphilis. Routine blood test is to check whether the human body’s complete blood count and other abnormalities, for clinical diagnosis of inflammation and anemia, etc. to provide the basis for laboratory tests. Syphilis is checked for syphilis-specific and non-specific antibodies. If the specific antibody test is positive, the diagnosis of syphilis can be confirmed. Antibodies are usually produced in the body 2 to 4 weeks after infection, and a positive blood test for syphilis-specific antibodies confirms the diagnosis of syphilis. Syphilis is a sexually transmitted disease caused by syphilis spirochete infection, after diagnosis of syphilis need to be early, adequate, regular treatment, etc., to prevent the further development of syphilis, stage II syphilis, stage III syphilis, preferred long-acting penicillin intramuscular injection. Regular serologic examination of syphilis is carried out after treatment. Blood routine can not check out syphilis, if suspected of syphilis infection, it is recommended to go to the hospital to improve the syphilis serology examination.