Cerebral infarction can take Angong Niuhuang Pills, which are mainly indicated for patients with large brainstem infarction as well as severe cases. In addition to somatic neurological dysfunction, such as hemiparesis, hemianesthesia, hemianopsia and speech dysfunction, patients with large infarction and brainstem infarction can have consciousness disorders, including drowsiness, lethargy or coma. A subset of patients can have specific disorders of consciousness, such as decortication, mutism syndrome or decerebrate tonicity, or even a vegetative state. Angong Niuhuang Pill has some waking effect and is mainly used in patients who are comatose, but also, in the acute phase. If the patient enters the posterior phase, the treatment effect is often poor. For patients with large cerebral infarction, if they are in coma, at the same time, compound musk injection and waking up the brain can be given, and Qingkai Ling can be given for treatment. When the patient’s condition is stable after 48-72 hours, rehabilitation treatment should be given as early as possible to prevent patients from complications and sequelae and reduce their mortality.