Patients with large right cerebral infarction will have severe left-sided hemiparesis, which is complete paralysis. On examination, the patient will be found to have zero muscle strength, complete immobility, extremely low muscle tone, diminished or completely absent tendon reflexes, and positive pathological signs in the lower limbs. Patients also often have a deficit of hemianesthesia, with reduced or absent pain and temperature sensation in the left hemianesthesia. There is also facial palsy and lingual palsy, which is usually central facial palsy. Patients will have significant cerebral edema after the onset of the disease, which may last 2-3 weeks. During this time the patient will develop symptoms of cranial hypertension, manifested by headache, nausea, vomiting, and sometimes significant impairment of consciousness, which may range from drowsiness to lethargy and coma. If patients do not respond well to treatment, they may be left with severe limb deficits and require prolonged bed rest or wheelchair assistance thereafter.