Thyroid nodules are raised foci on the thyroid tissue that are different from normal tissue, which is commonly known as a “lump” on the thyroid gland. Thyroid nodules can be benign or malignant, and some benign nodules can be left untreated with regular checkups. However, some nodules may be malignant and require timely intervention. What are the factors that indicate an increased risk of malignancy? The main risk factors for cancerous thyroid nodules are: 1. history of radiation exposure or exposure to radiation in the head during childhood or adolescence; 2. male nodules have a higher chance of becoming cancerous than females; 3. age <14 or >70 years old; 4. family history of thyroid cancer in the family; 5. regular checkups reveal that the nodules have significantly increased in size within a short period of time; 6. sudden onset of painful nodules; 7. hard texture, irregular shape, more stationary nodules, and more malignant nodules, Irregular shape and fixed nodules; 8. Persistent hoarseness, dyspnea, dysphonia, dysphagia, etc. Thyroid ultrasonography suggests that the characteristics of malignant changes in the nodule are: 1, hypoechoic nodules; 2, tiny calcification; 3, the lack of peripheral halo nodules; 4, irregular edges of the nodule; 5, blood flow signal disorders within the nodule; 6, the nodule aspect ratio of > 1 (height is greater than width). In general, if the patient has more than 2 of the above features at the same time or if one of the features is present in the hypoechoic nodule, the patient is warned to be aware of the possibility of malignant lesions.