Hashimoto’s thyroiditis can be treated with levothyroxine tablets and glucocorticoid therapy such as prednisone. In the early stage of Hashimoto’s thyroiditis, only thyroid autoantibodies are positive, and there are no clinical symptoms, and in the late stage of the disease, hypothyroidism may appear. Clinical treatment of Hashimoto’s thyroiditis mainly focuses on the symptoms of hypothyroidism and goiter compression. For hypothyroidism, levothyroxine tablets can be taken to replace the treatment. For rapid enlargement of the thyroid gland with localized pain or compression symptoms, glucocorticoid therapy such as prednisone can be given, and the dosage can be reduced after the symptoms are relieved. The above medications are recommended to be used under doctor’s supervision, and patients with confirmed diagnosis of Hashimoto’s thyroiditis are recommended to go to the hospital in time.