Acute gastric mucosal lesions mean acute inflammatory changes in the patient’s gastric mucosa, which are characterized by the presence of gastric mucosal erosions and often accompanied by gastric mucosal bleeding. It is mainly caused by non-steroidal anti-inflammatory drugs or food stress. Because of the presence of gastric mucosal erosion and gastric mucosal bleeding, this lesion can also be called acute erosive hemorrhagic gastritis, which is currently more commonly called. Acute gastric mucosal lesions is a customary name in the past, acute erosive hemorrhagic gastritis often causes upper gastrointestinal bleeding, but the bleeding is often relatively small. For the treatment of this disease, the first choice of drugs is acid inhibitors combined with drugs to promote mucosal repair, specific drugs need to consult a specialist.