Hepatitis B is possible to run for exercise, but activities should be reduced if the disease is in the severe active stage. Hepatitis B is the most common infectious liver disease in China. It can be manifested in many different states, such as hepatitis B virus carriers with normal liver function, in which case aerobic exercise can be carried out appropriately, including running, swimming and so on, which is very beneficial to the body, and it is a more respected form of exercise in our daily life. However, when hepatitis B develops into severe active hepatitis, or end-stage liver disease such as cirrhosis, liver cancer, etc., at this time we should pay attention to limiting activities, more bed rest. Especially when liver damage is severe, blood biochemical indicators such as alanine aminotransferase or glutamine aminotransferase indexes appear to rise, as well as appeared more serious gastrointestinal tract manifestations and some signs, it is not recommended to go to the exercise, heavy physical activity, to wait for the recovery of the indicators to stabilize, and then gradually and reasonably increase the amount of exercise.