Aminoglycoside antibiotics are a class of highly effective antibiotics, including natural antibiotics, such as streptomycin, kanamycin, gentamicin, neomycin, and minomycin, and artificial semi-synthetic antibiotics, such as etanercept and amikacin, etc. The role is to kill bacteria quickly, mainly by interfering with bacterial protein synthesis to play a bactericidal role, ineffective against anaerobic bacteria, only effective against bacteria that require oxygen. Especially the aerobic gram-staining negative bacilli have a powerful effect. Aminoglycoside antibiotics are mainly used to treat systemic infections caused by sensitive aerobic Gram-negative bacteria, including respiratory, gastrointestinal, urinary tract, meningitis, burns, wounds, bone and joint infections, etc. They can also be used orally in preparation for intestinal surgery, for hepatic coma, and as ointment, topical ointment or rinse for localized bacterial infections. Streptomycin and kanamycin also have anti-tuberculosis effects and can be used to treat tuberculosis.