Multiple ulcers in the duodenal bulb refers to multiple ulcers in the duodenal bulb observed during gastroscopy, instead of a single ulcer foci, with congested and edematous mucosa, covered with white moss, or even covered with blood crusts at the ulcer, and bulb ulcers of different sizes, about 0.2-1cm or even 2cm, have occurred. This problem is a more serious kind of ulcer, to find the cause, to see if the patient has H. pylori infection, whether the plain preference for smoking, drinking alcohol, whether meals are regular, whether the usual work life and living is regular, whether there are bad habits of staying up late, work pressure is also prone to multiple ulcers of the duodenal bulb. Therefore, the cause of multiple ulcers in the duodenal bulb should be searched for, and Helicobacter pylori infection should be eradicated and treated, and a healthy lifestyle, including eating on time and quitting bad habits such as smoking, alcohol and peppers, can help treat multiple ulcers in the duodenal bulb.