Infants with lupus erythematosus should choose appropriate treatment according to the cause of symptoms and diseases, such as adopting general treatment such as sun protection, warmth preservation and avoidance of stimulation, and medication such as oral glucocorticoid. The aim of SLE treatment is to suppress autoimmune reaction and inflammation in the short term, to restore and maintain the function of damaged organs and prevent tissue damage, to eliminate infection and its triggers, and to promote the recovery of immune-regulating function. 1. General treatment: Pay attention to sunscreen for infants, protect the skin, avoid skin irritation, and keep warm. 2. Drug therapy: the current treatment is based on oral glucocorticoid drugs as prescribed by the doctor, such as methylprednisone, dexamethasone, etc., in addition to injection of immunoglobulin also has a certain therapeutic effect. If other systems are involved, other symptomatic treatments should be prescribed. Found that infants have lupus erythematosus, parents need to take their children to the hospital in a timely manner to find out the cause, under the guidance of the doctor active treatment, so as not to delay the condition.