Diphtheria can be characterized by respiratory pseudomembrane, “barking” cough, etc., but bacteriological examination is needed to confirm the diagnosis, and should not be blindly diagnosed on its own. Diphtheria is an acute respiratory infectious disease caused by diphtheria bacillus, the clinical manifestations of sore throat, fever, general malaise and other symptoms, the throat and other parts of the gray-white pseudomembrane can be seen, the edge of the clear, not easy to peel, forcible peeling is the base of the naked surface of the hemorrhage, the patient can also be seen in the “barking” cough, hoarseness, the triple concave sign and other symptoms. As the above symptoms can also be seen in patients with purulent tonsillitis, thrush and other diseases, so we can not rely solely on the symptoms to diagnose, confirm the diagnosis still need to improve the bacteriological examination, can take specimens of pseudomembrane and mucous membrane junction smear, culture or fluorescent labeling specific antibody staining and other methods to detect. If symptoms suspected to be diphtheria appear, you should consult a doctor promptly to find out the cause and dispose of it.