Medications need to be considered when LDL cholesterol exceeds the reference value and lifestyle interventions alone are unsatisfactory. The normal reference range for LDL is less than or equal to 3.4 mmol/L, with 3.4 to 4.1 mmol/L being borderline and more than 4.1 mmol/L being elevated. Meanwhile, for people with risk factors such as hypertension, diabetes, coronary heart disease, cerebral infarction, etc., the LDL level should be less than 1.8mmol/L. Generally, when LDL cholesterol is elevated, lifestyle interventions should be taken first, such as avoiding a diet high in salt and oil, maintaining appropriate physical activity, and quitting smoking and drinking. If the above measures are not effective, or if the above risk factors are present at the same time, medication is needed. Medications such as ezetimibe, colesevelam, and statins such as atorvastatin can be used under medical supervision. It is recommended to consult a doctor for standardized treatment if necessary.