Metronidazole belongs to the class of nitroimidazole antibiotics, mainly treating diseases caused by anaerobic bacterial infections, like dental pulpitis, gynecological diseases, skin soft tissue infections and osteoarthritis, etc. In female gynecology, it is more effective for trichomoniasis, which can be taken orally or by intravenous infusion once a day without skin test, and can pass the blood-brain barrier, placenta or breast milk, and is prohibited during pregnancy and lactation. The main adverse reactions are gastrointestinal symptoms, such as nausea, vomiting, loss of appetite, etc. Large doses can cause convulsions. It is necessary to abstain from alcohol during the use of the drug, and abdominal pain, vomiting and headache can occur after drinking alcohol. It is recommended not to use it indiscriminately, and should be used according to the doctor’s prescription. After using the drug, if there is nausea, vomiting, abdominal pain, headache and rash, it is recommended to go to the hospital for examination and treatment in time.