Eugenol is the trade name, generic name is levothyroxine sodium tablets, used in the treatment of hypothyroidism, when the patient has β-sympathomimetic nerve effect, combined with cardiogenic disease, can be taken at the same time with bisoprolol tablets. 1. β-sympathomimetic effect, when the use of excessive levothyroxine sodium tablets, the patient may appear anxiety, agitation, tachycardia, unconscious movement, etc., then you can use β-blockers, such as bisoprolol tablets orally to improve the symptoms, and need to be adjusted under the guidance of the doctor levothyroxine sodium tablets dosage. 2. Combined with cardiogenic diseases, when suffering from thyroid disease combined with coronary heart disease, tachyarrhythmia, can use Bisoprolol to smooth the heart rate. Levothyroxine sodium tablets can be taken when tachycardia, angina, headache, flushing and other side effects. It is contraindicated in patients who are allergic to levothyroxine sodium tablets, untreated adrenal insufficiency, pituitary insufficiency, acute myocardial infarction, and acute myocarditis. Side effects of Bisoprolol include dizziness, headache, bradycardia, drop in blood pressure, etc. Bisoprolol is contraindicated in cardiogenic shock, atrioventricular block of II degree or higher, sick sinus node syndrome, bradycardia, low blood pressure, severe asthma. It is recommended that patients who need to apply levothyroxine sodium tablets and bisoprolol, under the guidance of a doctor.