Pectin generally refers to colloidal bismuth pectin, which, if taken in large doses over a long period of time, can lead to bismuth toxicity, which manifests itself as the skin turning dark brown. Colloidal bismuth pectin is a gastrointestinal mucosal protective drug, which is taken orally to form a sol in the stomach, forming a protective film to isolate gastric acid. It is suitable for the treatment of peptic ulcer, especially Helicobacter pylori-associated ulcer, and can also be used for chronic superficial and atrophic gastritis. As its main ingredient contains bismuth, long-term use of the drug may lead to bismuth poisoning, which is mainly manifested as nausea, vomiting, salivation (drooling) (drooling), pain in the tongue and throat, black feces or blood-stained feces, hemorrhagic dots on the skin and mucous membranes, and headache. In addition, a large amount of bismuth deposition in the body can cause bone lesions, such as humeral head osteoarthropathy. If you need to take it, it is recommended to go to a regular medical institution and use it under the guidance of a doctor.