The first thing you need to do is to get a good idea of what you are getting into. In addition to the above factors, genetic factors, dietary factors, emotional factors can lead to the aggravation of acne. 2, flat warts: the cause of its development is mainly related to human papillomavirus infection, can be transmitted through direct or indirect contact, local trauma, skin damage is an important triggering factor. In addition, there is also an important relationship with the body’s immunity, in the immune deficiency state, such as kidney transplants, malignant lymphoma, leukemia, lupus erythematosus patients, the probability of the onset of flat warts is higher.