Women supplementing folic acid during pregnancy can prevent neural tube malformations and other diseases in the fetus, and folic acid in pregnancy is usually recommended to be eaten half an hour after meals. After taking folic acid, there may be fear of food, nausea, bloating and other gastrointestinal reactions, pregnant women if you take folic acid before meals, easy to affect the appetite, eat after meals have less impact, so it is usually recommended that pregnant women should be half an hour after meals to take folic acid tablets. After taking folic acid, neurological adverse reactions such as difficulty concentrating, hyperactivity, and excitement may also occur. Folic acid is contraindicated in those with folic acid intolerance, and megaloblastic anemia caused by vitamin B12 deficiency cannot be treated with folic acid alone. Note that if large doses of oral folic acid are taken, the absorption of zinc may be affected. Note that folic acid should be used under the guidance of a doctor, avoid unauthorized use of medication to avoid adverse effects. If the symptoms continue to be unrelieved during the period of medication, it is recommended to consult a doctor in a timely manner, complete the relevant examinations, clarify the cause of the disease, and provide symptomatic treatment.