A one-and-a-half year old baby with a white patch on his face may be related to vitiligo, simple furfur, aphakic nevi and other diseases. 1. Vitiligo is an acquired pigment loss disease, the cause of its development is mainly related to genetic and autoimmune abnormalities. The actual vitiligo is usually a white or porcelain white pigmentation loss, the skin lesions can be alone, can also be in all parts of the body generalized, Wood’s lamp examination can help to clarify the diagnosis. 2. simple furfura, also known as white furfura, commonly known as the “worm spot”, the cause of its development and Malassezia furfur infection, but also with the sun, vitamin deficiency and intestinal parasites infection. Pityriasis simplex mainly occurs in the facial skin, manifested as round or oval hypopigmented spots. 3. Nevus pigmentosus: it is a congenital pigment loss disease, which can occur at birth or soon after birth, often manifested as irregular hypopigmented spots with fuzzy borders, which will expand proportionally with the development of the body. For the baby appeared facial white spots must be timely consultation, and under the guidance of the doctor to improve the relevant examination.