There are various causes of knee pain, and the first step is to identify the cause. For example, fractures caused by trauma, medial and lateral collateral ligament injuries, cruciate ligament injuries, osteoarthritis caused by infection, rheumatoid arthritis caused by autoimmune diseases, and proliferative lesions such as synovitis can all cause knee pain. For knee pain caused by trauma, the first step is to identify the fracture, dislocation or ligament injury. If the fracture has blood and swelling in the knee joint and the knee joint cannot be actively straightened, surgery is required for displaced fractures, while non-displaced fractures can be fixed in a cast and knee flexion and extension can be practiced as early as possible. For internal knee dislocations, the knee joint will be significantly limited, but usually it can be reset automatically or by manipulation or incision. In cases of ligament damage, cold compresses and compression bandages may be applied, and surgery may be performed depending on the patient’s condition. If the pain is caused by inflammation, non-steroidal anti-inflammatory drugs, such as acetaminophen, may be used for painful osteoarthritis. And non-steroidal anti-inflammatory drugs have better pain relief for mild to moderate pain. Secondly vitamin drugs can also be used for chronic pain. In addition to medication, physical therapy such as low-frequency pulsed electrotherapy, magnetic therapy, ultrasound therapy, etc. can also be administered. Other treatments such as acupuncture and tui-na, nerve block therapy, and minimally invasive interventions in Chinese medicine can also relieve pain. In addition, appropriate exercise is also inevitable. Exercise therapy can help promote blood circulation and reduce inflammatory response, and can be performed under the guidance of a professional doctor.