There exists no ointment specifically for the treatment of impetigo, and the treatment of impetigo includes topical medications and systemic medications. 1. Topical drugs: take sterilization, anti-inflammation and drying as the principle. If the pustules are not broken, 10% glycerite lotion can be used externally. When the pustules are big, the pustules should be extracted, and if the pustules are broken, the pustules can be washed and wetted with 1:5000 potassium permanganate solution or 0.5% neomycin solution, and then mupirocin ointment or fusidic acid ointment can be used externally. 2. Systemic medication: antibiotics should be used in a timely manner for those with generalized lesions and severe systemic symptoms, and antibiotics sensitive to Staphylococcus aureus can be selected, such as ceftazidime and levofloxacin, etc., and medication should be selected based on drug sensitivity test if necessary. At the same time, attention should be paid to the water electrolyte balance, if necessary, plasma transfusion or human blood gammaglobulin. Patients with impetigo should not use their own medication, but should go to the hospital, under the guidance of the doctor to standardize the use of medication.