The large pimples in the female private area may be due to folliculitis, warts, genital herpes, etc., and need to be treated with medication or surgery for the cause of the disease. 1. Folliculitis: Long-term wearing of breathable underwear, lack of cleanliness of the vulva and other factors lead to the accumulation of vulvar sweat stains and other secretions, followed by bacterial infection leading to inflammatory reaction of the hair follicles, which can lead to large pimples in the private parts of the female. You can use fusidic acid ointment, mupirocin ointment anti-infection treatment, and change to wear breathable underwear, pay attention to pubic hygiene. 2. Condyloma acuminatum: After infection with human papilloma virus (HPV), it causes cauliflower-like skin growths that resemble large pimples. It can be treated with topical 5% imiquimod cream or 5% fluorouracil ointment, etc. It can also be treated by liquid nitrogen freezing and laser. 3. Genital herpes: Herpes virus infection involves the female vulva, forming blister-like lesions locally on the vulvar skin, which can be treated with glycerine lotion, acyclovir ointment, vasiclovir ointment, etc. The above drugs should be used as prescribed by the doctor. All of the above medications should be used in accordance with medical advice. There are many reasons why women may have large pimples on their private parts, so it is recommended to consult a doctor in time to clarify the cause of the problem and standardize the treatment.