In intrahepatic cholestasis during pregnancy, the typical common clinical manifestations are: 1. Pruritus, without skin lesions, is the first symptom of ICP, with varying degrees of itching, often persistent, light during the day and intensifying at night. Pruritus usually begins on the palms of the hands and feet, then gradually extends to the proximal extremities and can even develop to the face, itching symptoms often appear before the abnormal results of laboratory tests, mostly relieved 24-48 hours after delivery; 2. Jaundice, 10%-15% of patients can develop mild jaundice, mostly after 2-4 weeks of pruritus, does not increase with the week of pregnancy, most of them show mild jaundice, which subsides within 1-2 weeks after delivery 1-2 weeks after delivery; 3. Skin scratching, ICP without primary skin lesions, pruritic skin with striated scratching and no abnormal findings when skin tissue is biopsied. With the above typical symptoms, liver function tests should be performed promptly at the hospital, and if the diagnosis of intrahepatic cholestasis in pregnancy is confirmed, treatment should be performed promptly.