Newborns who continue to cough after discharge from the hospital may be suffering from neonatal infectious pneumonia, acute upper respiratory tract infection, or acute infectious laryngitis. Generally, medication to control infection, oxygen therapy and tracheal intubation are used if necessary. 1. Neonatal infectious pneumonia: Infectious pneumonia after birth may present with wheezing and wet rales in both lungs. It needs to be treated by maintaining normal blood gases and fighting against pathogens. For example, herpes simplex virus causes pneumonia with acyclovir, chlamydia pneumonia preferred erythromycin and so on. At the same time to ensure water, electrolyte balance, as appropriate, input immunoglobulin to improve immunity. 2. Acute upper respiratory tract infection: more than 90% are caused by viral infection. Including general types of acute upper respiratory tract infection, herpes pharyngitis, pharyngeal conjunctival fever. If the infection is not serious, supportive treatment is enough. If it is caused by influenza virus, antiviral drugs such as oseltamivir can be used. 3. Acute infectious laryngitis: generally refers to acute diffuse inflammation of the laryngeal mucosa, caused by viral or bacterial infections, easy to appear barking cough, the use of glucocorticosteroids, such as hydrocortisone, etc. can reduce laryngeal edema, but also the use of antiviral drugs, antibacterial drugs (eg, cephalexin) to control the infection. Tracheal intubation and ventilator-assisted therapy can be used if severe hypoxia is present. If the newborn is discharged from the hospital and is still coughing, do not self-medicate your child, you need to seek medical treatment as soon as possible to avoid further attacks. All of the above medications should be used under a doctor’s supervision.